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2 DNA methylation DNA methylation, the addition of a methyl- group to one of the bases in the deoxyribonucleic acid chain, does not change the primary DNA sequence and it is therefore considered to be an epigenetic modification.

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Bacteremia without a known site of infection is the most common invasive clinical presentation of pneumococcal infection among children 2 years of age and younger, accounting for approximately 70% of invasive disease in this age group. Bacteremic pneumonia accounts for 12%–16% of invasive pneumococcal disease among children 2 years of age and younger. With the decline of invasive Hib …

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2 DNA methylation DNA methylation, the addition of a methyl- group to one of the bases in the deoxyribonucleic acid chain, does not change the primary DNA sequence and it is therefore considered to be an epigenetic modification.

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